The animated series centers on the life and adventures of the famous Geronimo Stilton, head of a media empire, a peaceful mouse and klutz extraordinaire, and his fearless young nephew Benjamin Stilton. Adventure always comes knocking on their door, launching them paws-first into capers in New Mouse City or in exotic locales around the world.

"Rancid rat hairs, the cat pirates are coming to town! They're planning on stealing New Mouse City's Statue of Liberty and taking it back to Cat Island. They think it's completely made of gold! My friends and I are determined to protect our city's precious symbol. But can we stop these fearsome felines?"--Page 4 of cover.

Sometimes a busy businessmouse like me needs a nice, relaxing vacation. But of all the rotten rats' luck -- every time I tried to get away, disaster struck. My aunt Dizzy Fur's mouse hole caught on fire, my office was flooded, and our printing press broke down! When I was finally ready to depart, all the good trips were booked up. I was stuck in a flea-ridden old hotel, sharing a room with a bunch of Gerbil Scouts! I couldn't wait to get back to my...

When my nephew, Benjamin, invited me to Career Day at his school, things did not turn out the way I expected. I caused a volcanic explosion, got tangled in the tunnel slide on the playground, and accidentally let the class's pet gecko out of its cage! Rat munching rattlesnakes -- how was I going to get myself out of this mess?

A curious case for Geronimo! Rancid ricotta! Something strange was happening in New Mouse City. Rodents were suddenly getting sick with stomachaches, hiccups and weird green warts and it seemed to be related to cheese! We mice eat a lot of cheese, so this was serious. My detective friend Hercule Poirat asked me to help him investigate. Could we solve this mystery and save our city?

Geronimo Stiltonoot wakes up to a terrible morning. Meteors are falling from the sky, and everyone in Old Mouse City has an awful stomachache! Geronimo must travel to the Cave of Memories to find the ancient shaman cure for his fellow cavemice. But dangers lurk on the journey -- can he make it back home safely?

When an evil professor begins threatening New Mouse City with terrible inventions, Geronimo Stilton is enlisted by local authorities to embark on a top-secret mission to outer space to thwart a nefarious plot.

When Geronimo agrees to be a caddie for his grandfather in a golf tournament, he and Special Agent OOK team up to prevent the theft of the Super Mouse Cup.

Geronimo Stilton visits Australia where he has an adventurous time dodging sharks and snakes, and getting lost in the Outback.

Geronimo Stilton recounts his trip to Niagara Falls when he accompanies some young mice there as part of a school field trip.