As the X-Men make their desperate attempt to get Hope to Utopia, the battle will cost them one of their own. This is the end of the line. The horror of what the X-Men face is fully revealed, and the reality sets in ... every single mutant on the planet is going to die. They cannot hold out any longer. And X-Force goes on their final mission.

When X-Force returns from the Age of Apocalypse with the Celestial Life Seed they discover their friend Angel is now Archangel, the heir to Apocalypse, and they must find the strength to destroy him before he destroys the world--if they can.

While one of the young X-Men breaks rank to join the adult Cyclops, Jean pushes her powers to the limit and is targeted by Mastermind.

The Uncanny X-Men have barely had time to find their footing as a team before they must face the evil Dormammu! Can Magik match the demon lord's sorcery? Is she even on the X-Men's side anymore? The Uncanny X-Men have seen what can happen with no control over their powers. It cannot happen again. One mutant learns that once you leave the X-Men, the real world can be a punishing place. Another learns just what it means to be an X-Man. But what, exactly,...

Collects Extraordinary X-Men #13-16, Annual #1. An ancient evil stirs in the periphery of Limbo, consuming mystical realms — and little does Magik suspect that the X-Men's newest charge is drawing this World-Eater straight to X-Haven! Meanwhile, Colossus rampages across Earth as a Horseman of Apocalypse! Can Nightcrawler and Iceman wrest their friend from his evil influence? As the World-Eater bears down on Limbo, everything Magik cares about

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The Xavier Institute for mutant education and outreach prepares to foster the next generation of heroes and diplomats. Jubilee is asked to become mentor to a special group of these students.

Collects Uncanny X-Men (2016) #16-19, Annual #1. The X-Men confront the Inhumans in the most uncanny conflict of all! Since the discovery that the Terrigen Mist — the key to unlocking an Inhuman's hidden potential and powers — is lethal to mutants, the X-Men and Inhumans have been locked in a cold war. But now things are heating up, and about to boil over, as the X-Men are forced into drastic steps to ensure the future of their species!

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"Professor X's darkest secret revealed! What happens when the skeletons in your closet finally break down the door and come looking for you? The X-Men are about to find out! The mutant community is in turmoil, and the X-Men are bearing the brunt of this New World Order. Amid the chaos, a new enemy awakens, one whose very existence will haunt the founding members of the X-Men like nothing has before. Who is this new threat? How is he tied to a long-hidden...

As Magneto's Acolytes amp up their attacks on Homo sapiens everywhere, the X-teams join forces to put an end to the villainous zealots' mad crusade once and for all. But has their leader, messianic madman Magneto, returned from the dead? And as a mysterious and fatal disease begins creeping through the mutant community, which X-Man will lose a loved one - and buckle under the strain? Tensions come to a head in the most shocking way possible, culminating...